Immune

HLA B27 is an allele group of the HLA B gene, which encodes an MHC class I molecule that presents peptides to CD8 T cells, located...

HLA B57 is an allele group of the HLA B gene, an MHC class I gene in the major histocompatibility complex on chromosome 6p21.33. T...

BTK Bruton Tyrosine Kinase on chromosome Xq22.1 encodes a cytoplasmic tyrosine kinase essential for B cell receptor signaling and ...

STAT3 Signal Transducer and Activator of Transcription 3 on chromosome 17q21.2 encodes a transcription factor activated by Janus k...

ACE2 on chromosome Xp22.2 encodes angiotensin converting enzyme 2, a membrane bound carboxypeptidase discovered in 2000 that conve...

HLA DQ2 and HLA DQ8 are MHC class II molecules, encoded by combinations of the DQA1 and DQB1 genes in the HLA region on chromosome...

IL2RG on chromosome Xq13.1 encodes the common gamma chain, a subunit shared by the receptors for several interleukins, including I...

ADA on chromosome 20q13.12 encodes adenosine deaminase, an enzyme of purine metabolism that converts adenosine and deoxyadenosine ...

FOXP3 on chromosome Xp11.23 encodes a forkhead family transcription factor that is the master regulator of regulatory T cells, a s...

NOD2 on chromosome 16q12.1 encodes an intracellular pattern recognition receptor that detects muramyl dipeptide, a fragment of the...