Clotting

F8 on chromosome Xq28 encodes coagulation factor VIII, a cofactor for factor IXa in the intrinsic tenase complex that activates fa...

F9 on chromosome Xq27.1 encodes coagulation factor IX, a vitamin K dependent serine protease that, once activated, forms a complex...

VWF on chromosome 12p13.31 encodes von Willebrand factor, a large multimeric glycoprotein made by endothelial cells and megakaryoc...

F5 on chromosome 1q24.2 encodes coagulation factor V, a cofactor that, once activated, greatly accelerates the conversion of proth...