Oncogene

KRAS on chromosome 12p12.1 encodes a small GTPase in the RAS MAPK signaling pathway that cycles between an active GTP bound state ...

EGFR Epidermal Growth Factor Receptor on chromosome 7p11.2 encodes a receptor tyrosine kinase of the ErbB family that activates th...

PIK3CA on chromosome 3q26.32 encodes p110 alpha, the catalytic subunit of class I phosphatidylinositol 3 kinase, which generates t...

ERBB2, also called HER2, on chromosome 17q12 encodes a receptor tyrosine kinase of the epidermal growth factor receptor family. HE...

BRAF on chromosome 7q34 encodes a serine threonine kinase in the RAS RAF MEK ERK signaling pathway, which relays growth signals fr...

MYC on chromosome 8q24.21 encodes c MYC, a transcription factor that regulates a vast number of genes involved in cell growth, met...

ABL1 on chromosome 9q34.12 encodes a non receptor tyrosine kinase involved in cell differentiation, division, adhesion, and the re...

RET on chromosome 10q11.21 encodes a receptor tyrosine kinase that is essential for the development of the enteric nervous system ...

TERT on chromosome 5p15.33 encodes the catalytic subunit of telomerase, the enzyme that adds repetitive DNA sequences to chromosom...