Signaling

JAK2 on chromosome 9p24.1 encodes Janus kinase 2, a cytoplasmic tyrosine kinase that transmits signals from receptors for erythrop...

STAT3 Signal Transducer and Activator of Transcription 3 on chromosome 17q21.2 encodes a transcription factor activated by Janus k...

BMPR2 on chromosome 2q33.1 encodes bone morphogenetic protein receptor type 2, a serine threonine kinase receptor of the TGF beta ...

NOTCH1 on chromosome 9q34.3 encodes a transmembrane receptor of the Notch signaling pathway, a highly conserved system of direct c...

DMPK on chromosome 19q13.32 encodes myotonic dystrophy protein kinase, a serine threonine kinase expressed in muscle, heart, and b...

FGFR3 on chromosome 4p16.3 encodes fibroblast growth factor receptor 3, a receptor tyrosine kinase that acts as a brake on the gro...

MC4R on chromosome 18q21.32 encodes the melanocortin 4 receptor, a G protein coupled receptor in the hypothalamus that is a key pa...